Search results for "Anti ageing"

showing 2 items of 2 documents

Anti-ageing gene therapy: Not so far away?

2019

Improving healthspan is the main objective of anti-ageing research. Currently, innovative gene therapy-based approaches seem to be among the most promising for preventing and treating chronic polygenic pathologies, including age-related ones. The gene-based therapy allows to modulate the genome architecture using both direct (e.g., by gene editing) and indirect (e.g., by viral or non-viral vectors) approaches. Nevertheless, considering the extraordinary complexity of processes involved in ageing and ageing-related diseases, the effectiveness of these therapeutic options is often unsatisfactory and limited by their side-effects. Thus, clinical implementation of such applications is certainly…

0301 basic medicineAgingviral vectorsComputer scienceProcess (engineering)Genetic enhancementBiochemistry03 medical and health sciences0302 clinical medicineGenome editingAnimalsHumansMolecular Biologyageing-related diseaseHealth spanGene Editingageing-related disease; anti-ageing medicine; gene editing; gene therapy; health span; viral vectorsGenetic TherapyAnti ageinghealth spangene therapyClinical Practice030104 developmental biologyNeurologyRisk analysis (engineering)anti-ageing medicine030217 neurology & neurosurgeryGenome architectureBiotechnologyAgeing research reviews
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A scientific approach to anti-ageing therapies: state of the art.

2008

A lasting dream of human beings is to reverse or at least postpone ageing. During the last years, an increasing number of scientific meetings, articles, and books have been devoted to anti-ageing therapies. This subject, full of misleading, simplistic, or wrong ideas, is very popular among the general public, whose imagery has been fascinated by all possible tools to delay ageing, getting immortality. Here, we discuss anti-ageing strategies aimed not to rejuvenate but to slow ageing and delay the onset of age-related diseases. These approaches should be able to substantially slow down the ageing process, extending our productive, youthful lives.

PharmacologyGerontologyAGEINGIMMUNOSENESCENCEALZHEIMER'S DISEASECARDIOVASCULAR DISEASESDIETAgingbusiness.industrymedia_common.quotation_subjectSubject (philosophy)Environmental ethicsImmortalityAnti ageinghumanitiesDietState (polity)Alzheimer DiseaseCardiovascular DiseasesImmune SystemDrug DiscoveryMedicineHumansDreambusinessmedia_commonCurrent pharmaceutical design
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